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Whatever we do, performance does matters to make it successful. A good performance is a result of a positive morale and our sincere efforts. One gets great amount of personal satisfaction after employing such efforts. But the problem comes when we begin to think about results rather then concentrating on our efforts. This is a fact which is true irrespective of the task we are indulged in. A bit strangely, this fact is true even with our performance on bed while having sexual intimacies with our partner. This is a psychological problem, sometimes men continues to think of their sexual performance and the extent to which they can satiate their partners. The fear of failure is one major factor leading to sexual dissatisfaction while intercourse. As a result more then often such people fails to get proper penis erection leading unsatisfied female partner. Various sexual therapies are recommended to sexual efficiency and to overcome the problems pertaining to sex. Another sexual disorder which has been a nightmare for millions of men around the world is ED or erectile dysfunction. This generally occurs in old age or due to damage to nerves, arteries, muscle or tissue that are required for getting a hard and erect penis. Ailments like diabetes or neurological disease are mainly responsible for such damages. But with treatment becoming readily available more and more people are opting for potency pills. Viagra, being one of the most reliable names under this category is a highly popular drug. Even after the emergence of new drugs, Viagra is still preferred by most people due to its affordable price and effectiveness. So if you want to get rid of your performance woes, don’t wait, go ahead and buy Viagra online from a trusted pharmacy. It can also be bought from a cheap Viagra pharmacy in your locality at unmatched prices. pnis enlargement excercises penile enlargement pills review vimax free penis enlargement exercise natural penis enlagement technique penile enlargement pills product plastic surgery penis enlagement penis enlarement operation herbal penis enargement pills

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A person who is sexually very active and satisfied means he will live a long and healthy life. This is a proven fact, a man with happy sexual life lives longer compared to those who are unable to reach that level of sexual satisfaction. Perhaps this is a logical deduction from the new found fact that impotence is not a disease in itself, rather a symptom to more serious health conditions. Researches on the anatomy of erection explain that penile erection is sustained by trapping the blood in the penis. Erectile dysfunction is not subjected to low libido or ejaculation problems; rather, it is mainly a problem with the blood flow into the penis. And blood flow is affected by many factors like ageing, diabetes mellitus, hypertension or high blood pressure, substance abuse, low testosterone levels, cigarette smoking, cardiovascular diseases, nerve or spinal cord damage and medications. There are mental problems associated with ED; these are stress, depression and anxiety. If these physical and mental conditions do not occur, men will obviously be able to live long and will also have a sexually active life. People are going gaga about PDE5 inhibitors and their unending potential to save the human race from several physical conditions. Viagra, Levitra and Cialis have captivated the medical intelligentsia who are investigating the possibilities of PDE5 inhibitors as life saving drugs. When it comes to Levitra, Vardenafil Hydrochloride, scientists have agreed upon its molecular strength and impact on cardiovascular conditions and hypertension. Reports show that Levitra is far more effective in patients of erectile dysfunction with diabetes as well as high blood pressure. Doctors, scientist and researchers as well as the patients who have used all the PDE5 inhibitor drugs available in the market, have accepted that Levitra can give a strong erection under tough conditions. If a person is suffering from erectile dysfunction for no matter what physical conditions, he should try Levitra at least for once. There is no reason for anyone to live with depression for the rest of his life…with a shattered ego and battered manhood. It was medically proved that Vardenafil can even help in erectile dysfunction induced by the medications used to treat hypertension. Levitra is a medicine that can invigorate your sexual life and give you ultimate bliss. But before you use Levitra, it is important for you to consult a doctor and get a thorough physical check up done, to understand the real cause behind your sexual dysfunction. Based on your physical condition, your doctor will prescribe Levitra dosage for best results. Again, if you wish to know in detail about erectile dysfunction and Levitra and its functionalities, there are websites available on which you can read a lot about Levitra and the cures it offers. It is time to say ‘good bye’ to your erectile dysfunction and enjoy your sexual life to the fullest and live longer. Why worry when Levitra is here! penis enlarement surgery picture natural penis enlargment penis enlargment cream free penis enhancement technique best penis enlargement pill enlargement erection penis pills vimax free penis enlargement technique com enlargement pnis pnis pump best penis enlargement pill

"Masturbation ... is not approved of the Lord nor this church, regardless of what may be said by those whose 'norms' are lower", President Kimball of the Church of Jesus Christ of Latter-Day Saints (1981) "Every sperm is sacred. Every sperm is great. If a sperm is wasted, God gets quite irate." Monty Python's The Meaning of Life. A quote often used by various churches in an effort to contain illicit acts amongst its people. Every sermon on masturbation would quote it, atleast all the sermons I have heard. Under the circumstances, is it difficult to imagine masturbation as one of the biggest taboos in our society? Even today? Scientific education has done a little to change it. Does that mean men and women don't masturbate? Certainly not. 99% of men and 70% of women masturbate according to various studies. The problem lies in the acceptance of the fact that you masturbate. Let me tell you a story... a story about you. One night you were sitting alone in your appartment eating pizza. You decided to check out some new sites on the net while you eat. So you log on to your ISP and start surfing. Inadverantely, you come across some piece of pornography(yes, the net is quite full of it!) Looking at those erotic (and often downright nasty photos) you feel a tingling between your legs. One thing leads to another and you end up spoiling your underpants. Now let me tell you another story. One night you were sitting alone in a bar drinking beer. And then a most gorgeous person enters the bar. The person that causes tingling between your legs just looking at him or her. You decide that you can't let go of this oppurtunity to get to know this wonderful creation of god. So you move towards this person and start small talk. One thing leads to another and you end up in your appartment. Whether you are a woman or a man, the next morning you wouldn't be jumping with joy in the first case. When you go out in the evening to meet your friends, you would not tell them about the hot site you found and how you jerked off to it. Nevertheless, in the second case, you would be telling anyone who cared to listen how you had the most wonderful experience of your life last night. Why? Well, maybe because self pleasure is, well, nothing special. You can do it anytime you want. Ofcourse seducing the person of your dreams is quite an accomplishment. No wonder you need an audience. But what if you have a friend like me. A friend who is crazy enough to ask you did you wank off yesterday night? Was it good? What would you do then? Would you tell your friend about the hot site and your experience? Would you simply say, "Yeah! It was great! What about you?" Or would you pretend nothing had happened and lie... something like you were somewhere else yesterday night, or maybe lead your friend to believe you got lucky with someone? I am guessing you would do the latter. Most certainly you won't acknowledge the act of masturbation. Rather you would evade the question and change the topic. And when your friend tells you about a hot conquest the same night, you would wish you had a bowl of water in which you could drown. Shame and guilt would come over you and you would change the topic in double quick time. Are you crazy? Noway! You are just one of the majority. And quite a majority at that! Way more majority that what George Bush had in the last elections! The reason - social conditioning! You are just like the boy who ran out of the cinema hall that was screening an adult film (mind you, he had no business of being there in the first place! But all the cinemas care about is the sale of their tickets!) Later in the day, the friend who had been at the movies with him, caught up with him and asked, "Why in the hell's name did you run out?" The boy answered, "My mom said that if I watched a woman getting naked I would turn to stone. And damn you Harry, a part of me was already turning into stone!" Unluckily, the social conditioning is wrong. It is as wrong as the social condition in 18-19th century India, where widows were forced to burn alive with their husbands. As wrong as the church was in burning Galileo for implying the Earth was not the centre of the universe. Lily Tomlin put it best, "We have reasons to believe that man first walked upright to free his hands for masturbation!" If god didn't want us to masturbate, maybe we would still be walking like dogs and horses! The social conditioning is a result of numerous myths, lies and scams perperated by numerous individuals for personal benefit. Unfortunately, this conditioning is like a hard nut, very tough to crack. However, with effort and chanelising your energies, you can break it. Remember, the nuts that crack the hardest, are often the ones that taste the best! You must be wondering, how the hell does it matter if you feel guilty about masturbation. Why should you spend time breaking this casing? Certain psychologists believe that guilt conscious, whether sexual guilt or in any other form, is the most destructive element for your mental health. Others believe it is one of the most destructive. But the greatest effect of guilt conscious in my experience has been a lack of confidence in self. Now you are an intelligent reader. I don't need to explain you the importance of self confidence. Be it your career, relationships or any other aspect of life, lack of confidence can bring your downfall. Now I am not implying that should you start to feel more comfortable about masturbation, you would succeed in all aspects of life. But it would be a nice step to take. An useless guilt that should, and can be eradicated from your mind. Remember, an ocean is made of small droplets of water. Get rid of a drop at a time and in due time, the ocean would be empty! Ofcourse it would take several millenia! Luckily, you don't have an ocean full of guily! Just some naggings here and there! The first step towards eradication of this guilt is knowledge. There are thousands of myths around masturbation. Most of them perperated by religion, unfortunately. But some perperated by scam runners. Lets take a look at the most important ones. 1. Masturbation is against the will of god. Bullshit. At one point the church considered anyone who was overtly passionate to his wife an adultrater. Follow that teaching and your wife would be committing adultery! Several clergymen have gone on record to say that not only the church's teachings about sexuality were unrelated to the scriptures, but that they caused more harm than good amongst people. Besides, nowhere in the religious teachings of any major religions is masturbation considered wrong. 2. Masturbation will cause impotency. Most males and even some females seem to think so. Wrong again. Lets tackle the males first. It is understandable that seeing their sperm flow out of their body, they think it may end sometime. Well, it will end one day... maybe when you are 100 years old. But until then don't worry. Your sperm bank is quite unlike Standard Chartered. You have unlimited credit here! Sperm is a completely renewable resource, renewable on an hourly basis! For women, well, there is no basis in the theory. Probably perperated by old ladies who never had an orgasm in their entire life! 3. Masturbation causes acnes, hair loss, skin diseases. This one is my favorite. Mainly because it is one of the better scams of all times! Your social conditioning would have you believe that masturbation is bad for your health. But bad how? No one would give you a satisfying answer! Now some scam artists saw this as an good oppurtunity to sell their products like hair growth lotions, etc. Since most people start masturbating during their teens, (the times of acne and other skin problems), they would have you believe that this is caused by masturbation! Unluckily for them, this is as untrue as the sun rising from the west! Masturbation has no physical side effects! 4. Masturbating will make you thin and skinny! Then there would be no need for diet pills and fitness regimes my friend! And most certainly 70% of USA wouldn't be overweight! 5. Only Kids masturbate! Why would you say that? I wonder! Well quite untrue, most adults masturbate... yup even after marriage! 6. Masturbation is for males. And it is for 70% of the women too. Thats right, two thirds of all females masturbate! 7. Only losers masturbate! Another of my favorites. Just goes to show just how much of a taboo is masturbation! First thing, 99% of males and 70% of females have masturbated atleast once in their lives. Now that is a hell of a lot of losers don't you think! Nothing more that I can add really... this is really the epitome of insecurity amongst people regarding self pleasure. 8. Masturbation is for homosexuals. Wow. Where did that one originate! Someone must make a etymology of these myths, would make for an interesting read! Just as untrue as all these myths, masturbation and homosexuality have nothing in common. Some people masturbate to their fantasies of opposite sex, others to their fantasies of same sex. Thats it. 9. Masturbation will make you blind! Others claim that masturbation is bad for your eyesights. However, their claims are unsupported by facts and medical advice. I suggest you talk to your general physician and he will explain you what a load of bull this is. 10. Masturbation changes the shape of your penis Well, it does make it rock hard. But believe me, once you orgasm, the hardness is gone! So no. Masturbation has absolutely no effect on how your penis looks. There are loads more of these myths circulating around the world. If you have a query about masturbation, ask me, I would happily lay your fears to rest. My email is advice@pornographytimes.com Now lets move on in an attempt to get rid of your guilt. Clearly, all the reasons that made masturbation such a taboo are baseless. So why should you feel guilty about something that is normal and actually healthy? Healthy? Yes that too! This January, I recieved an email from a woman who had some major problems in her marriage. Due to her career and that of her husband, their sexual life was inexistant. Both held jobs in big MNCs and were frequently out of town. Sometimes, they would see each other once a month! Nevertheless, they were very much in love. Her problem was, that inspite of all their love, they were getting into petty fights with each other. The woman was even experiencing problems during work, getting angry for no apparent reasons, shouting on her team. Her temperament was a creation of the stress caused by extensive work and lack of pleasurable activities. Add to that sexual frustration. My advice to her was twofold. First, I told her that she would have to slow down, and so should her husband. They must make time for their hobbies, maybe try and get in some physical exercise when they could. Most certainly, they needed to see more of each other. They should onsider talking off a couple of days and just be together. Second, while she was alone, she should consider fantasy therapy. Namely, reading erotic novels, watching erotic movies... exciting herself and eventually masturbating as regularly as she could. Three months later, I recieved a thank you letter from her. Apparently she had put my advice to practice (which is quite rare!) and it had actually helped. (Which is not so rare!) How did masturbating help her? Because most of her problems arose from stress and lack of physical activities. And masturbation, like sex, is the perfect medicing. When you orgasm, your mind gets cleared of the regular day to day problems. Your body gets excited and the blood flow increases. Sometimes, you even sweat! A complete and perfect exercise for those with lack of time! The next step in getting rid of your guilt is self belief. Something, no outsider can help you with. Here is what I would counsel. Read as many articles on the internet as you can relating to masturbation. Just so that you know that I am not bullshitting you. Any queries you have, don't be afraid to ask me or another sex advisor on any of the reputed websites. Remember, the first step is knowledge and the second step is belief. And knowledge leads to belief. 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Sex is in the brain and the brain sends signal of fulfillment and pleasure to the body after an orgasmic sexual activity. But there are millions of men who fail in having the immense pleasure of love making due to erectile dysfunction. Erectile dysfunction (ED) commonly called impotence is a physical condition in men’s health when he is unable to achieve or maintain an erection sufficient for fulfilling his sexual needs or the needs of his partner, consistently over a period of time. The cure for such a sexual health condition was unthinkable. Couples in love whose female partners stuck by them in their difficult period had to rely on fantasy sex and enact their own fantasy sexual stories. But the men always had a sense of guilt for not being able to deliver to the needs of his partner’s sexual fantasies. In 1998, Pfizer Pharmaceuticals manufactured the first drug Viagra, for the treatment of erectile dysfunction. Viagra (sildenafil) is an oral prescription drug which is to be used only after consulting a physician. Its active ingredient Sildenafil citrate enables many men with ED to respond to sexual stimulation. When a man is sexually aroused, the arteries in the penis relax and widen, allowing more blood to flow into the penis, resulting in an erection. Thus men using Viagra were able to revitalize their sex life like never before. But, like all good things, Viagra also has its share of liabilities. Viagra intake without proper clinical examination (to the body’s resistance capacity for active sex) and probabilities for drug interactions and side-effects might be dangerous. Men should not be carried away by their sexual fantasies and have Viagra just for the lust of it. If you suspect yourself to be suffering from impotence, do not hesitate to approach your doctor or you can collect sufficient Viagra information over the Net. With the advent of Viagra, erectile dysfunction has become a thing of the past. Earlier, men suffering from ED always had the inferiority complex of not been able to live-up to his partner’s female sexual fantasies. This often created sexual disharmony in a relationship. He sometimes failed to understand that a woman’s sexual fantasies need not always be her wishes. Sexual fantasies can be a healthy aid if used with comfort, concern and mutual understanding. Viagra has over the years revolutionized the concept of failure. Men using Viagra for treating erectile dysfunction has become more comfortable and confident of his sexual prowess. It will not be exaggerating to say that - Viagra has transformed an impotent man into a Viagra man. forum magna rx penis enlarement operation best pennis enlargement pills top rated penis elargement pills penis enargement secret vigrx side effects top rated penis enlargment pills herbal natural penis enlarement best penis enlargement pill

Believe it or not, there is a natural ingredient from Europe that can help change the way your legs feel and the way you feel about the circulation in your legs. Whether we realize it or not, the circulation in our legs can have a huge influence on how we feel and what we do everyday and perhaps even more so every evening. The comfort level of our legs, or better said, their discomfort level at the end of the day can adversely affect our social life and fitness activities - not to mention adversely affecting our sleep. If our legs felt better perhaps we would find it easier to do the things we'd love to do, but find it so difficult to muster the motivation. As if the way our legs can feel at the end of day isn't challenging enough, the changes in the circulation in our legs as we age can seem even more hopeless and discouraging. Now add to that the seeming conspiracy among fashion designers to have us exposing even larger portions of our aging legs and we have a problem that over 80 million Americans with varicose veins understand all too well. (1). Unfortunately, about half of all American women will develop varicose or spider veins at some point in their lives (2). Not only are they unsightly, these leg problems can also cause significant discomfort. Typically, varicose veins are characterized by bulging, blue, sometimes painful and inflamed veins that appear primarily in the calves and thighs. Spider veins, on the other hand, show up as a web of fine lines that can make your legs look like a road map. While age and heredity play a role in the development of varicose and spider veins, weight gain, pregnancy, menopause and the use of hormone replacement therapy can also trigger these vein problems. Making matters worse, chronic inactivity, standing for long periods of time or habitually crossing your legs can make you more prone to injured veins (2). Conventional treatments include surgical stripping, injecting the veins with a chemical irritant or zapping them with lasers. While these approaches can remove existing varicose or spider veins, they will not prevent new ones from developing, since these high-tech treatments do not address the underlying problem of poor circulation. Worse yet, these procedures can also cause infection, scarring, nerve damage and pain (26). If these radical treatments are not an option for you, you'll be happy to hear that there is a natural approach that not only improves the appearance of these ropy, bulging veins, it also fosters leg health to prevent future problems. Veins Explained To understand how varicose veins develop, you need to know a little bit about how blood moves through the body. Essentially, there are two types of major circulatory vessels in the body: the arteries, which channel blood from the heart to the extremities, and the veins, which bring blood from the extremities back to the heart. Of all the veins in your body, leg veins work the hardest to carry blood back to the heart. To accomplish this difficult task, your legs are equipped with specially designed one-way valves that keep the blood moving in the right direction. As efficiently as these valves work, your legs still fight a constant battle against the natural pull of gravity. If the veins can't move the blood efficiently or the one-way valves that prevent the blood from backwashing fail to close properly, blood collects in the legs. This pooling of blood then stretches the vein, causing swelling and injury to the vein's walls (3). Depending on the extent of the enlargement, these veins can show up as either spider or varicose veins. Spider veins are broken capillaries and small veins that appear as jagged red, blue or purple lines on the surface of the skin. While they aren't painful, they can be extremely unattractive. Varicose veins, on the other hand, are thick veins that run deeper beneath the skin. They are far larger and much less attractive than spider veins - and they can make your legs feel fatigued, heavy, achy or even itchy. Varicose veins can also cause burning, throbbing, cramping and restlessness. While these conditions aren't usually dangerous, severe cases can lead to chronic venous insufficiency - a persistent inability of the leg veins to adequately return blood back to the heart (4). Varicose veins are also associated with the development of skin ulcers or a chronic inflammation of a vein - a condition known as phlebitis. Phlebitis is often accompanied by formation of a blood clot, a dangerous situation since the clot can move from the leg vein and travel to the lungs (2). Get a Leg Up with Diosmin Your strategy for battling vein problems naturally is twofold: improving circulation and strengthening the vein walls. The first and simplest measure to improve blood flow is to counteract gravity. Standing or sitting all day makes it harder for blood to move up from the legs and back to the heart. But taking a few minutes to rest with your legs higher than your heart each day allows gravity to help return blood to the heart. Getting in shape can also help relieve varicose and spider veins - and it can even prevent new ones from forming. As we age we lose muscle tone, which adversely affects the health of our legs. Yet adopting a consistent exercise program promotes good circulation and can help to keep our leg muscles, and the blood vessels in our legs, toned. Walking, weight training, low-impact aerobics and swimming strengthen the legs and circulatory system, and help to reduce the throbbing and aching often associated with varicose veins. What you eat can also ease unsightly veins. A low-fat diet filled with fruits, vegetables, beans, legumes and whole grains add key nutrients and fiber to your diet. Eating a fiber-rich diet reduces the chances of constipation which can contribute to varicose veins. Constipation restricts the blood as it returns to the torso through the deep veins in the legs. Straining to have a bowel movement closes off the deep veins in the legs and restricts the flow of blood as it returns to the torso. As the blood backs up, it takes another course through superficial veins, thus the blue streaks in the legs. Eating a fiber-rich diet alleviates and prevents constipation, helping to avoid the damage to the vascular system that can result. In addition to fiber, a diet high in fruits and vegetables also ensures adequate intake of nutrients and phytonutrients, which also help tonify the blood vessels. As a bonus, a healthy diet and exercise program can also jump-start weight loss - an important consideration since carrying too much weight creates extra pressure on your heart and blood vessels, interfering with healthy circulation (2). To strengthen the veins themselves, take a tip from the Europeans. From Austria to France to Italy, women and their doctors have relied on Diosmin for more than 30 years to treat circulatory problems affecting the legs - and with good reason. Diosmin is a unique bioflavonoid derived from citrus fruits and is closely related to other citrus bioflavonoids such as hesperiden, quercetin, and rutin (5). Clinical trials have shown that Diosmin is highly effective in boosting circulation and strengthening the veins in the legs (5). Not only does this improve existing varicose and spider veins, it can also reduce the likelihood of future problems. What makes Diosmin so amazing is its power to specifically target the blood vessels in the legs. Diosmin improves both blood vessel elasticity and microcirculation while relieving pain and inflammation by inhibiting pro-inflammatory prostaglandins and thromboxanes (21,24). Because of its direct action on the integrity of vein walls, Diosmin also reduces the amount of fluid that leaks out of them (21,22). Diosmin's protective benefits do not stop there. Because it is a potent anti-oxidant, Diosmin decreases lipid peroxidation and reduces free radical damage that can undermine vein health (23, 27). In one clinical trial, people who suffered from pain and swelling due to varicose veins experienced significant improvement in their symptoms after taking Diosmin for a few months (6). A review of studies also found that, among more than 5,000 patients with vein disorders, the vast majority not only saw a reduction in their discomfort, they actually saw the swelling in their calves and ankles disappear (7). Across the board, research shows that a daily dose of 500 to 1,000 mg of Diosmin improves the health of leg veins and brings tremendous relief from pain, night cramps and leg heaviness (8,9,10,11). Both short- and long-term use of this highly effective natural ingredient comes without any side effects. It is also so safe that you need not worry about adverse interactions of Diosmin with drugs, foods, lab tests or interactions with diseases or conditions. (5). Help for Hemorrhoids Because Diosmin reduces swelling and bolsters vein health, it can also help people suffering with hemorrhoids - those uncomfortable varicose veins that form in the lower rectum and anus. Along with making it painful to sit, hemorrhoids can itch, bleed or protrude - and almost half of all Americans suffer from them by the time they turn 50 (12). Extensive research conclusively shows that Diosmin can safely alleviate the pain, inflammation and bleeding of hemorrhoids (13,14,15). Best of all, it offers quick relief, often working its magic within a week or two (16). Plus, Diosmin reduces the risk of a relapse (17). Diosmin for Cancer? While no one questions Diosmin's efficacy for treating varicose and spider veins or hemorrhoids, scientists have begun exploring other ways this potent flavonoid may boost health. Their main focus - cancer prevention - especially oral and skin cancers. Researchers haven't conclusively identified the cancer-fighting component in Diosmin, but preliminary experiments show that this flavonoid inhibits the proliferation of cancer cells (18). In two studies pitting Diosmin against other flavonoids like rutin, grapeseed extract and red wine, Spanish investigators found that Diosmin was considerably more effective at reducing the number of metastatic melanoma cells (a potentially deadly type of skin cancer cells that spread through the body) than any of the other flavonoids tested (19,20). Other studies have found that Diosmin puts the brakes on the spread of cancer cells in the mouth (25). Although it could be years before science conclusively proves Diosmin's cancer benefit, this nutrient can't be beat for supporting vein health. Along with taking supplemental Diosmin, there are several simple strategies you can employ to encourage healthy circulation. Eating a high-fiber, anti-oxidant rich diet and getting plenty of exercise can help keep veins in top form. And remember to take a break and put your feet up every now and again. References: 1. American Society for Dermatoloic Surgery. 2. National Women's Health Information Center. U.S. Department of Health & Human Services. 3. American College of Phlebology. 4. Society for Vascular Surgery. 5. Diosmin Monograph. Alternative Medicine Review. 2004;9(3):308-311. 6. Ting AC, et al. Clinical and hemodynamic outcomes in patients with chronic venous insufficiency after oral micronized flavonoids therapy. Vascular Surgery. 2001;35(6):443-447. 7. Ramelet AA. Daflon 500 mg: symptoms and edema clinical update. Angiology. 2005;56 Suppl 1:S25-S32. 8. Bergan JJ. Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg. Angiology. 2005; 56 Suppl 1:S21-S24. 9. Nicolaides AN. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003;54 Suppl 1:S33-S44. 10. Smith PC. Daflon 500 mg and venous leg ulcer: new results from a meta-analysis. Angiology. 2005; 56 Suppl 1:S33-S39. 11. Jantet G. Chronic venous insufficiency: worldwide results of the RELIEF study. Reflux assessment and quality of life improvement with micronized Flavonoids. Angiology. 2002;533:245-256. 12. National Institutes of Health. 13. Lyseng-Williamson KA, et al. Micronised purified flavonoids fraction: a review of its use in chronic venous insufficiency, venous ulcers and haemorrhoids. Drugs. 2003;63(1):71-100. 14. Meshikhes AW. Daflon for haemorrhoids: a prospective, multi-centre observational study. Surgeon. 2004;2(6):335-338. 15. Kecmanovic D, et al. PHLEBODIA (diosmine): a role in the management of bleeding nonprolapsed hemorrhoids). Acta Chirurgica Iugoslavica. 2005;52(1):115-116. 16. Diana G, et al. Activity of purified diosmin in the treatment of hemorrhoids. La Clinica Terapeutica. 2000;151(5):341-344. 17. Misra MC, et al. Randomized clinical trial of micronized flavonoids in the early control of bleeding from acute internal haemorrhoids. British Journal of Surgery. 2000;87(12):1732-1733. 18. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042. 19. Martinez C, et al. Treatment of metastatic melanoma B16F10 by the flavonoids tangeretin, rutin, and diosmin. Journal of Agricultural and Food Chemistry. 2005;53(17):6791-6797. 20. Martinez C, et al. The effect of the flavonoids dioxmin, grapeseed extract and red wine on the pulmonary metastatic B16F10 melanoma. Histology and Histopathology. 2005;20(4):1121-1129. 21. Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-56. 22. Cyrino FZ, et al. Micronization enhances the protective effect of purified flavonoidsfraction against postischaemic microvascular injury in the hamster cheek pouch. Clinical and Experimental Pharmacology & Physiology. 2004;31(3):159-162. 23. Bergan JJ, et al. Therapeutic approach to chronic venous insufficiency and its complications: place of Daflon 500 mg. Angiology. 2001;52 Suppl 1:S43-7. 24. Katsenis K. Micronized purified flavonoids fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency. Current Vascular Pharamcology. 2005;3(1):1-9. 25. Browning AM, et al. Flavonoid glycosides inhibit oral cancer cell proliferation - role of cellular uptake and hydrolysis to the aglycones. Journal of Pharmacy and Pharmacology. 2005;57(8):1037-1042. 26. National Women's Health Information Center. U.S. Department of Health and Human Services, Office on Women's Health. 27. Villa P, et al. Protective effect of diosmetin on in vitro cell membrane damage and oxidative stress in cultured rat hepatocytes. Toxicology. 1992;73:179-189.